ALTERATIONS OF HAEMATO-BIOCHEMICAL PARAMETERS DUE TO GASTRO-INTESTINAL HELMINTHS INFESTATION IN SHEEP

Title: ALTERATIONS OF HAEMATO-BIOCHEMICAL PARAMETERS DUE TO GASTRO-INTESTINAL HELMINTHS INFESTATION IN SHEEP

Authors: Sunil Arora, Vikash Kumar Sharma, Anandita Srivastava and Pradeep Kumar

Source: Ruminant Science (2018)-7(2):265-268.

Cite this reference as: Arora Sunil, Sharma VK, Srivastava Anandita and Kumar Pradeep (2018). Alterations of haemato-biochemical parameters due to gastro-intestinal helminths infestation in sheep. Ruminant Science 7(2): 265-268.

Abstract

Present study was conducted to compare the changes occurring in haemato-biochemical parameters of sheep naturally suffering from gastro-intestinal helminth infection. The blood samples were collected from 35 infected and 20 non-infected sheep aged 6 months to 1.5 years. The blood samples were taken in ethyleneditetraacetic acid (EDTA) coated and plain vials for haematological and biochemical studies. Mean±SE values of haematological parameters viz. haemoglobin (Hb, g/dl), packed cell volume (PCBV, %), erythrocyte sedimentation rate (ESR, mm/hr), total leukocyte count (TLC, X103/cumm) were 7.92±0.432, 24.9±1.910, 0.29±0.0601, 13.43±0.918, respectively and neutrophils, eosinophils, basophils, lymphocytes and monocytes (%) were 28.48±1.530, 5.34±0.513, 0, 66.82±1.389 and 5.08±0.391, respectively in infected sheep whereas the (mean±SE) values of same haematological parameters were 9.69±0.446, 32.76±3.105, 1.06±0.097, 11.43±0.876 and 32.90±2.470, 3.45±0.439, 0, 61.39±1.896 and 5.1±0.463, respectively in non-infected sheep. Mean±SE values of biochemical parameters of albumin, globulin and total serum protein (g/dl) were 1.91±0.312, 3.38±0.423 and 5.29±0.258, respectively in infected sheep whereas values of same biochemical parameters were 3.17±0.293, 3.17±0.594 and 6.39±0.533, respectively in non-infected sheep. It was observed that in infected sheep Hb, PCV and ESR were reduced significantly and number of lymphocytes, eosinophils and monocytes were increased significantly. While total serum protein and albumin were decreased significantly but serum globulin was increased non-significantly in infected sheep.

References

Amulya G, Sudharani R, Ismail Shareef M and Gopinath SM (2014). Haemato-biochemical changes in sheep suffering from gastrointestinal parasitism. Indian Journal for Field Veterinarians 10(2):20-22.

Bhat MS, Sudhan NA and Mir AQ (2004). Haemato-biochemical studies in sheep infected with natural gastrointestinal nematodiasis. Indian Journal of Veterinary Medicine 24(2):76-78.

Bordoloi G, Jas R and Ghosh JD (2012). Changes in the haemato-biochemical pattern due to experimentally induced haemonchosis in Sahabadi sheep. Journal of Parasitic Disease 36(1):101-105.

Chedge R, Dixit AK and Dixit Pooja (2013). Prevalence of gastrointestinal parasites in goats at Adhartal, Jabalpur. Ruminant Science 2(2):155-159.

Dixit Pooja, Rao MLV, Dixit AK and Shukla PC (2016). Prevalence of gastrointestinal parasites in goat kids in Jabalpur. Ruminant Science 5(1):39-42.

El-Sayed M, El-Ramady RA and Tawfiw SA (2003). Effect of Mirazid on Fascioliasis and blood chemistry in sheep. Egypt Journal of Agriculture Research 81(2):785-796.

Garedaghi Y, Rezaii-Saber AP, Naghizadeh A and Nazeri M (2011). Survey on prevalence of sheep and goats lungworms in Tabriz abattoir, Iran. Advance Environment Biological 5:773-775.

Gupta SK and Singla LD (2012) Diagnostic trends in parasitic diseases of animals. In: Veterinary Diagnostics: Current Trends. Eds: RP Gupta, SR Garg, V Nehra and D Lather. Satish Serial Publishing House, Delhi, pp 81-112.

Jas R, Datta S and Ghosh JD (2008). Haemato-biochemical impact of gastrointestinal nematodosis in Bengal goat. Journal of Veterinary Parasitology 22:21-26.

Kramer JW (2000). Normal hematology of cattle, sheep and goats. In: Schalm’s veterinary hematology. Eds: BF Feldman, JG Zinkl and NC Jain, 5th Edn,  Lippincott Williams and Wilkins, Philadelphia. pp 1075-1084.

Kumar S, Jakhar KK, Singh S, Potliya S, Kumar K and Pal M (2005). Clinicopathological studies of gastrointestinal tract disorders in sheep with parasitic infection. Veterinary World 8(1):29-32. 

Lotfy HS, Mahmoud SM and Abdel-Gawad MA (2003). Some studies on Fascioliasis in Mid-Egypt. Agriculture Research 81(2):209-227.

Matanovic K, Severin K, Martinkovic F, Simpraga M, Janicki Z and Barisicz J (2007). Hematological and biochemical changes in organically farmed sheep naturally infected with Fasciola hepatica. Journal of Parasitology Research 101(6):1463-1731.

Mohammed DS (2000). Effect of helminth parasites of farma animals. Thesis PhD submitted to Faculty of Veterinary Medicine, Cairo University.

Nwosu CO, Madu PP and Richards WS (2007). Prevalence and seasonal changes in the population of gastrointestinal nematodes of small ruminants in the semi-arid zone of north eastern Nigeria. Journal of Veterinary Parasitology 144:118-124.

Odesanmi SO, Lawal RA and Ojokuku SK (2010). Haematological effect of ethanolic fruit extract of Tetrapleura tetraptera in male Dutch white rabbits. Research Journal Medicine Plant 4:213-217.

Omran HH and El-Kholony KH (2003). The influence of nitroxynil on clinical, biochemical and haematological parameters in Egyptian buffaloes affected with liver flukes in Sharkia goveronerate. Egyptian Journal Agriculture Research 81(2):739-751.

Osuigwe DI, Nwosu C and Oguni JO (2007). Preliminary observation on some haematological parameters of juvenile and heterobranchus longifilis fed different dietary level of raw and boiled jackbean (Canavalea ensiformis) seed meal. Conference on International Agriculture Research for Development 1-6.

Pal Papri,  Chatlod LR, Avasthe RK and Prasad A  (2013). Gastrointestinal helminths of goats in a subtropical and high humid zone of Sikkim, India. Ruminant Science 2(2):149-153.

Pandit S, Jas R, Ghosh JD and Moi S (2009). Impact of naturally occurring gastrointestinal nematodosis on serum protein concentration in Garole sheep. Environment and Ecology 27(4):1526-1529.

Qamar MF and Maqbool A (2012). Biochemical studies and serodiagnosis of haemonchosis in sheep and goats. Journal of Animal and Plant Science 22(1):32-38.

Ram PK and Kumar Amit (2013). Incidence of helminths infection in bovine calves. Ruminant Science 2(1):75-76.

Singh R, Bal MS, Singla LD and Kaur P (2017a). Detection of anthelmintic resistance in sheep and goat against fenbendazole by faecal egg count reduction test. Journal of Parasitic Diseases 41(2):463-466.

Singh E, Kaur P, Singla LD and Bal MS (2017b). Prevalence of gastrointestinal parasitism in small ruminants in western zone of Punjab, India. Veterinary World 10(1):61-66.

Singla LD (1995). A note on sub-clinical gastro-intestinal parasitism in sheep and goats in Ludhiana and Faridkot districts of Punjab. Indian Veterinary Medical Journal 19:61-62.

Snecdecor GW and Cochron WG (1994). Statistical Methods. 6th Edn, Oxford and IBH Publishing Company, Calcutta.

Teleb FD, Soliman EK and Abd El-Khalek TMM (2007). Effect of Fascioliasis on haematological, serum biochemical and histopathological changes in sheep. Egyption Journal of Sheep and Goat Sciences 2(2):15-34.