Successful therapeutic management of onion toxicosis induced hemolytic anaemia in bovine

14-Title: Successful therapeutic management of onion toxicosis induced hemolytic anaemia in bovine

Authors: AU Bhikane, KS Kedar, RK Jadhav, SG Chavhan and YM Wankhede

Source: Ruminant Science (2019)-8(2):209-212

How to cite this manuscript: Bhikane AU, Kedar KS, Jadhav RK, Chavhan SG and Wankhede YM (2019). Successful therapeutic management of onion toxicosis induced hemolytic anaemia in bovine. Ruminant Science 8(2):209-212.


Onion (Allium cepa) poisoning is an acute afebrile condition observed in farm animals due to the accidental ingestion of a large number of onions and clinically characterized by haemoglobinemia, haemoglobinuria and anaemia. Three cases of bovine including two bulls and one buffalo were presented with a history of the feeding of onions for three days. Clinical examination revealed passage of coffee-coloured urine, dullness, inappetence, suspended rumination, pallor of mucosae, straining during defaecation, scanty faeces, subnormal body temperature, increased heart rate and respiration. Haemato-biochemical analysis showed a severe decrease in Hb, TEC and PCV values with marginally elevated serum total bilirubin, urea nitrogen, and creatinine. Blood smear examination showed the absence of haemoprotozoan infections and the presence of numerous Heinz bodies. The cases were confirmed for onion toxicosis based on history, clinical signs and haemato-biochemical analysis and successfully treated with Vitamin E & Se @ 10 ml SC for 5 days, Dextrose 20% @ 500 ml slow IV BID for 5 days, B complex @ 7.5 ml IM SID for 10 days and haematinic bolus @ 1 PO BID for 20 days. Gradual improvement in treated animals was observed over a period of 5 days with the disappearance of haemoglobinuria, resumption of feed intake, rumination and absence of straining during defaecation.


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