18-Title: Bovine pituitary specific transcription factor 1(PIT-1) gene polymorphism in indigenous cattle of North East India vis-a-vis crossbred cattle

Authors: Keyolenu Yore, P Mayengbam, NS Singh and TC Tolenkhomba

Source: Ruminant Science (2020)-9(1):87-90.

How to cite this manuscript: Yore Keyolenu, Mayengbam P, Singh NS and Tolenkhomba TC (2020). Bovine pituitary specific transcription factor 1(PIT-1) gene polymorphism in indigenous cattle of North East India vis-a-vis crossbred cattle. Ruminant Science 9(1):87-90.

Abstract

The study was conducted to explore the polymorphism in bovine Pituitary Specific Transcription Factor 1 (PIT-1) gene in 210 indigenous cattle of North East India viz. Meitei san (Manipur), Zobawng (Mizoram), Tho Tho (Nagaland), Lakhimi (Assam), Tripuri (Tripura), Meghalaya and Crossbred cattle. Two different variants of PIT-1 gene viz. A and B were detected using PCR-RFLP. The B allele was predominantly (0.776) prevalent among local cattle of North East India and slightly lower (0.650) in crossbred cattle. Among the genotypes, BB genotype was found in high frequency among the local cattle of North East India. While the genotype BB was comparatively low in the crossbred population. The AA genotype was almost absent in the indigenous cattle population. The population conforming to equilibrium indicated lack of selection pressure in these cattle population.

References

Ahmadi MM, Mirzaei A, Sharifiyazdi H, Hajibemani A and Rowshan A (2015). Pituitary-specific transcription factor 1 (PIT-1) polymorphism and its association on milk production and some reproductive performance in Holstein dairy cows. Revue de Medecine Veterinaire 166(5-6):127-131.

Aytekin Ý and Boztepe S (2013). Associations of PIT-1 gene polymorphism with milk yield and composition traits in Brown Swiss cattle. Journal of Animal and Plant Sciences 23(5):1281-1289.

Bodner M, Castrillo JL, TheilL LE, Deerinck T, Ellisman M and Karin M (1988). The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein. Cell 55:505-518.

Carrijo SM, Regitano LCA, Alencar MM and Toral FLB (2003) Influência das variantes genéticas do gene PIT-1 sobre características de produção de carne em animais da raça Canchim. Proceedings of the 49º Congresso Nacional de Genética, Águas de Lindóia, SP, Brasil. 

deMattos KK, Del-Lama SN, Martinez ML and Freitas AF (2004). Association of bGH and PIT-1 gene variants with milk production traits in dairy Gyr bulls. Pesquisa Agropecuaria Brasileira 9(2):147-150.

Di Stasio L, Sartore S and Alberta A (2002). Lack of association of GH1 and POU1F1 gene variants with meat production traits in Piedmontes. Animal Genetics 33:61­64.

Dierkes B, Kriegesmann B, Baumgartner BG and  Brening B (1998). Partial genomic structure of the bovine PIT1 gene and characterization of a HinfI transition polymorphism in exon 6. Animal Genetics 29:405.

Dobson H, Smith R, Royal M, Knight CH and Sheldon IM (2007). The high-producing dairy cow and its reproductive performance. Reproduction in Domestic Animals 2:17-23.

Dybus A, Szatkowska I, Czerniawska-Pi¹tkowska E, Grzesiak W, Wójcik J, Rzewucka E and Zych S (2004). PIT1-HinfI gene polymorphism and its associations with milk production traits in polish Black-and-White cattle. Archive fur Tierzucht Dummerstorf 47(6):557-563.

Faure R and Morales C (2003). La pubertad de la hembra bovina: I. aspectosfisiologicos. Revista de Salud 25(1):13-19.

Javanmard A, Asadzadeh N, Banabazi MH and Tavakolian J (2005). The allele and genotype frequencies of bovine pituitary specific transcription factor and leptin genes in Iranian cattle and buffalo populations using PCR-RFLP. Iranian Journal of Biotechnology 3(2):104-108.

Livestock Census (2012). The 19th Livestock Census- 2012 All India Report. http://dahd.nic.in/sites/default/files/Livestock%20%205.pdf. Accessed on 23rd April 2017.

Moody DE, Pomp D and Barendse W (1995). Restriction fragment length polymorphism in amplification products of the bovine PIT1 gene and assignment of PIT1 to bovine chromosome 1. Animal Genetics 26:45-47.

Mukesh M, Sodhi M, Sobti RC, Prakash B, Kaushik R, Aggarwal RAK and Mishra BP (2008). Analysis of bovine pituitary specific transcription factor­HinfI gene polymorphism in Indian zebuine cattle. Livestock Science 113(1):81­86.

Renaville R,  Gengler N,  Parmentier I,  Mortiaux F,  Massart S,  Bertozzi C,  Burny A and Portetelle D (1997). Pit1 gene Hinf I RFLP and growth traits in double­muscled Belgian Blue cattle. Journal of Animal Science 75(1):146.

Woollard J, Schmitz CB, Freeman AE and Tuggle CK (1994). Rapid communication: HinfI polymorphism at the bovine PIT-1 locus. Journal of Animal Science 72:3267.

Yeh FC, Yang RC, Boyle TBJ, Ye ZH and Mao JX (1997). POPGENE the user friendly shareware for population genetic analysis. University of Alberta, Canada.

Zhao Q, Davis ME and Hines HC (2004). Associations of polymorphisms in the PIT-1 gene with growth and carcass traits in Angus beef cattle. Journal of Animal Science 82:2229-2233.