5-Title: Clinico-diagnostic and therapeutic investigations on pneumonia in cattle

Authors: CS Jaibhaye, AU Bhikane, PS Masare and AV Bhonsle

Source: Ruminant Science (2020)-9(1):25-32.


How to cite this manuscript: Jaibhaye CS, Bhikane AU, Masare PS and Bhonsle AV (2020). Clinico-diagnostic and therapeutic investigations on pneumonia in cattle. Ruminant Science 9(1):25-32.


Pneumonia is a multi-factorial respiratory disorder commonly found in cattle and is causing heavy economic losses to farmers due to increased calf mortality, costs of medication, production losses and decreased draft ability in bullocks. Hence the present study was undertaken to investigate epidemiological, clinico-diagnostic and therapeutic aspects of pneumonia in cattle. On screening 1211 cattle reported to TVCC, COVAS, Udgir for different ailments, 46 animals were found positive for pneumonia, suggestive of overall prevalence of 3.80%. The higher prevalence of pneumonia was observed in young male cattle put to heavy work and exposed to climatic stress during monsoon. The typical signs of pneumonia included fever, nasal discharge, dyspnoea, coughing, chest pain and abnormal lung sounds. Haemogram showed significant leucocytosis accompanied by neutrophilia with non- significant changes in other blood parameters. On radiographic examination of thorax, a variable degree of congestion and diffuse consolidation of lungs was noticed. The faecal examination revealed negative for lungworm larvae infestation. The bacteria isolated from nasal swab were identified as Staphylococcus sp., Streptococcus sp., E. coli, Corynebacterium sp., Klebsiella sp., Mannheimia haemolytica, Brevundimonas sp., Pseudomonas sp.. The results of antibiotic sensitivity test of isolated organisms revealed highest sensitivity to gentamicin (87.50%), followed by ceftriaxone plus tazobactam and enrofloxacin (58.33% each), amoxicillin plus sulbactam (54.16%), ceftiofur sodium (50.00%), chloramphenicol (45.83%), ciprofloxacin (41.66%), moxifloxacin (33.33%), oxytetracycline (16.66%) and complete resistance to penicillin. Thirty six pneumonia affected cattle were randomly divided into four treatment groups viz., Group A (gentamicin @ 4 mg/ kg), Group B (enrofloxacin @ 5 mg/ kg),   Group C (moxifloxacin @ 5 mg/ kg ) and Group D (ceftiofur @ 1.6 mg/ kg). All 36 treated cattle clinically cured within 3 to 15 days, indicating 100 per cent recovery rate. The evaluation of comparative efficacy revealed that gentamicin is superior to other drugs in the treatment of pneumonia in cattle.


Ananthakrishna LR, Kamboj Aman, Saini Mohini and Gupta PK (2015). Characterization of extracellular domain of glycoprotein e gene of an Indian isolate of bovine herpes virus-1. Ruminant Science 4(1):15-20.

Bateman KG, Bair J, Slocombe JO, Leslie KE, Curtis RA and Menzies PI (1986). Verminous pneumonia in adult dairy cows in southern Ontario due to Dictyocaulus viviparus. Canadian Veterinary Journal 27:233-236.

Cruickshank R, Duguid JP, Marmion BP and Swain RHA (1975). Medical Microbiology Vol. II, 12th Edn, Churchil Livingstone, New York. pp 202-203.

Donkersgoed JV, Carl S, Ribble Leona G, Boyer and Hugh GG and Townsend (1993). Epidemiological study of enzootic pneumonia in dairy calves in Saskatchewan Canadian Journal of Veterinary Research 57:247-254.

El-Tahawy Abdelgawad Salah and Mostafa Ibrahim Ahmed (2015). Prevalence, risk factors and cross sectional epidemiology for some selected diseases and syndromes affecting Rahmani sheep with particular spotlight on their economic consequences. Ruminant Science 4(2):159-165.

Isabelle M, Gilles F, Luc Breton, Pierre H, Guy B and Laurent B (2008). Radiographic detection of thoracic lesions in adult cows: A retrospective study of 42 cases (1995-2002) Canadian Veterinary Journal 49:261-267.

Jared DT, Robert WF, Terry WL, Douglas LS and Anthony WC (2010). The epidemiology of bovine respiratory diseases: What is the evidence for predisposing factor? Canadian Veterinary Journal 51:1096-1102.

Kurcubic V, Dokovic R, Vidanovic D, Sekler M, Matovic KZ, Ilic Z and Stojkovic J (2013). Bovine respiratory disease complex: Viral and bacterial pathogens in Serbia. Biotechnology in Animal Husbandry 29:3743

Lekeux P and Art T (1988). Effect of enrofloxacin therapy on shipping fever pneumonia in feedlot cattle. Veterinary Record 123:205-207.

Loneragan GH, Dargatz DA, Morley PS and Smith MA (2001). Trends in mortality ratios among cattle in US feedlots. Journal of American Veterinary Medical Association 219:1122-1127.

Lopez A and Bildfell R (1992) Pulmonary inflammation associated with aspirated meconium and epithelial cells in calves. Veterinary Pathology 29:104-111.

Machhaliya MH, Patel BJ, Joshi DV, Raval SH and Patel JG (2015). Pathomorphological studies on spontaneously occurring pulmonary lesions in buffaloes (Bubalus bubalis). Ruminant Science 4(1):51-53.

Makhdoomi DM, Mohsin AG, Noor AT and Zahid UN (2013). Therapeutic management of respiratory infections in large and small ruminants-A clinical study of 96 animals. Intas Polivet 14(I):88-92.

Mandal Ravi Shankar Kumar, Lekshman Aishwarya, Rana Ankush, Gaykwad Chandrakiran, Kumar Surender, Suthar NA, Vadhana Prasanna, Mondal DB and Dixit SK (2016). Diagnosis and therapeutic management of hemorrhagic septicemia: A case report in 4 buffaloes. Ruminant Science 5(2):287-289.

Mulei CM, Gitau GK and Mbuthia PG (1995). Cause of calf mortality in Kabet area of Kenya. Onderstepoort.  Journal of Veterinary Research 62:181-185.

Pal RS and Bamania MK (2016). Studies on mortality rate in preweaning kids of Sirohi goat. Ruminant Science 5(1):91-93.

Pirie HM, Petrie  L, Pringle CR, Allen EM and Kennedy GJ (1981). Acute fatal pneumonia in calves due to respiratory syncytial virus. Veterinary Record 108:411-416.

Portis E, Lindeman C, Johansen L and Stoltman G (2012). A ten-year study of antimicrobial susceptibility of bacteria that cause bovine respiratory disease complex- Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in the United States and Canada. Journal of Veterinary Diagnostics and Investigations 24:932-44.

Priyadarshi BH, Joshi DV, Patel BJ, Raval SH and Patel HA (2013). Pathomorphology of spontaneously occurring pulmonary lesions in sheep (Ovis aries). Ruminant Science 2(1):31-35.

Kumar Praveen, Kumar Ashok, Sharma Anshu and Yadav Rajendra (2015). Bovine respiratory disease complex in buffaloes-A study of associated bacterial isolates and their antibiograms. Intas Polivet 16(2):189-192.

Radostits OM, Gay CC, Hinchclif KW and Constable P (2010). Veterinary Medicine. 10th Edn,  Sounders Elsevier Edinburgh, London. pp 508-517.

Sen S and Albay MK (2003). Aetiology of respiratory tract infections in calves and evaluation of treatment with combination of amoxicillin and clavulanic acid. Indian Veterinary Journal 80:519-21.

Shakespeare AS (2012). Aspiration lung disorders in bovines: A case report and review. Journal of South African Veterinary Association 83(1):1-7.

Singh P and Singh KP (2009). Neonatal calf pneumonia and its therapeutic management. Intas Polivet 10(2):280-281.

Smith RA (2000) Effects of feedlot disease on economics, production and carcass value. Bovine Practitioner 33:125-128.

Smith BP (2009). Large Animal Internal Medicine. 4th Edn, Mosby Publishers, Missouri. pp 602-607.

Snedecor GM and Cochran WC (1994). Statistical Methods.  8th Edn, Iowa State University Press, Ames, Iowa.

Tripathi N, Jadon NS and Jaiswal S (2012). Therapeutic efficacy of epipleural blockage for the treatment for aspiratory pneumonia in buffalo calves. Indian Journal of Veterinary Medicine 32(1):27-29.

Van der fels- Kierx HJ and Sorensen JT (2001). An economic model to calculate farm-specific losses due to bovine respiratory disease in dairy heifer. Preventive Veterinary Medicine 51:75-94. 

Van der fels- Klerx HJ, Horst HS and Dijikhuizen AA (2000). Risk factors for bovine respiratory disease in dairy young stock in the Netherlands: The perception of experts. Livestock Production Science 66(1):35-46.

Verschooten F, Oyaert W and Drubbel R (1974). Radiographic diagnosis of lung diseases in cattle. Veterinary Radiology 15(I):49-59.

Verma BK, Mahajan NK, Mali G and Dhiya JP (2004). An epidemiological study on bovine haemorrhagic septicemia in Haryana. Indian Veterinary Journal of Animal Research 38(1):14-19.

Wadhwa D, Wadhwa, DR, Kumari Meena and Katoch (2006) Therapeutic efficacy of enrofloxacin (Quintas) in neonatal calf pneumonia. Intas Polivet 7:54-55.