1-Title: Antimicrobial resistance: Indian scenario especially in veterinary sector

1-Title: Antimicrobial resistance: Indian scenario especially in veterinary sector
Authors: Shriya Rawat, Jyoti Misri, Asha Kumari Verma and ZB Dubal
Source: Ruminant Science (2024)-13(1):1-12.

Abstract

How to cite this manuscript: Rawat Shriya, Misri Jyoti, Verma Asha Kumari and Dubal ZB (2024). Antimicrobial resistance: Indian scenario especially in veterinary sector. Ruminant Science 13(1):1-12.
Abstract
Global antibiotic consumption and antimicrobial resistance in human and livestock are increasing tremendously. Several factors are involved in developing antimicrobial resistance by using different mechanisms by the pathogens. In the present scenario, food safety, nutritional security, inadequate sanitary facilities and antimicrobial resistance in various pathogens particularly ESBL-producing E. coli (including several ESBL genotypes), NDM and MRSA in human beings and animals are the few challenges. If AMR is not addressed well in time, it may cause havoc in the future. Limited reports are available on the detection of AMR pathogens from food-producing animals and their products from India. Therefore, control/regulations over the counter sale of antimicrobials, development of SOP/standard treatment guidelines for common infectious diseases, awareness, personal hygiene and sanitation, improving immunization coverage; rapid outbreak response, and continuous surveillance of AMR pathogens for monitoring resistance in human, animals and aquaculture is must.
References
Anukampa, Bi Shagufta, Sivakumar M, Surender Kumar, Agarwal RK, Bhilegaonkar KN, Kumar A and Dubal ZB (2017). Antimicrobial resistance and typing of Salmonella isolated from street vended foods and associated environment. Journal of Food Science and Technology 54(8):2532-2539.
Bajpai T, Pandey M, Varma M and Bhatambare GS (2017). Prevalence of TEM, SHV and CTX-M Beta-lactamase genes in the urinary isolates of a tertiary care hospital. Avicenna Journal of Medcine 7(1):12-16.
Bandyopadhyay S, Banerjee J, Bhattacharyya D, Samanta I, Mahanti A, Dutta TK, Ghosh S, Nanda PK, Dandapat P and Bandyopadhyay S (2018). Genomic identity of fluoroquinolone-resistant blaCTX- M-15-type ESBL and pMAmpC beta-lactamase producing Klebsiella pneumoniae from buffalo milk, India. Microbial Drug Resistance 24(9):1345-1353.
Bbosa GS, Mwebaza Norah, Odda John, Kyegombe DB and Ntale M (2014). Antibiotics/antibacterial drug use, their marketing and promotion during the post-antibiotic golden age and their role in emergence of bacterial resistance. Health 6(5).
Berger-Bachi B (1994). Expression of resistance to methicillin. Trends in Microbiology 2:389-393.
Bhargava K, Wang X, Donabedian S, Zervos M, da Rocha L and Zhang Y (2011). Methicillin-resistant Staphylococcus aureus in retail meat, Detroit, Michigan, USA. Emerging Infectious Diseases 17:1135.
Bhati Taruna, Chhabra Rajesh, Yadav Rahul, Charaya Gaurav and Kataria Anil Kumar (2021). Antimicrobial resistance profiling of Staphylococcus aureus isolated from mastitic milk of bovine and dairy environment from arid and semi-arid regions of India. Ruminant Science 10(1):57-66.
Bhoi DB, Sutaria TV, Suthar DN and Dadawala AI (2013). Antibiotic sensitivity pattern of repeat breeder cow cervico-vaginal mucous. Ruminant Science 2(1):71-72.
Bradford PA (2001). Extended-spectrum beta-lactamases in the 21st century: Characterization, epidemiology and detection of this important resistance threat. Clinical Microbiology Review 14:933-951.
Brower CH, Mandal S, Hayer S, Sran M, Zehra A, Patel SJ, Kaur R, Chatterjee L, Mishra S, Das BR, Singh P, Singh R, Gill JPS and Laxminarayan R (2017). The prevalence of extended-spectrum beta-lactamase-producing multidrug-resistant Escherichia coli in poultry chickens and variation according to farming practices in Punjab, India. Environ Health Perspect 125(7):077015.
CDC (Centers for Disease Control and Prevention) (2013). Antibiotic resistance threats in the United States. Atlanta
Chambers HF (1997). Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clinical Microbiology Reviews 10:781-791.
Chandrasekaran D, Venkatesan P, Tirumurugaan KG, Nambi AP, Thirunavukkarasu PS, Kumanan K, Vairamuthu S and Ramesh S (2014). Pattern of antibiotic resistant mastitis in dairy cows. Veterinary World 7(6):389-394.
Chellat MF, Raguž L and Riedl R (2016). Targeting Antibiotic Resistance. Angewandte Chemie International Ed in English 1:55(23):6600-26.
Choudhary Sangita, Joseph Bincy, Sharma Sandeep Kumar, Shekhawat Surendra Singh and Mohammed Nazeer (2022). Detection of extended-spectrum beta-lactamase and carbapenemase resistant Klebsiella pneumoniae in bovine milk. Ruminant Science 11(1):93-100.
CLSI (Clinical and Laboratory Standard Institute) (2012). Performance standards for antimicrobial susceptibility testing; Twenty-second informational supplement. Clinical and Laboratory Standards Institute, Wayne, PA 2012.
Correia S, Poeta P, Ebraud MH, Luis Capelo J and Igrejas G (2017). Mechanisms of quinolone action and resistance: Where do we stand? Journal of Medical Microbiology 66:551-559.
Crisostomo MI, Westh H, Tomasz A, Chung M, Oliveira DC and de Lencastre H (2001). The evolution of methicillin resistance in Staphylococcus aureus: Similarity of genetic backgrounds in historically early methicillin susceptible and resistant isolates and contemporary epidemic clones. Proceedings of the National Academy of Sciences 98:9865-9870.
Cuny C, Friedrich A, Kozytska S, Layer F, Nubel U, Ohlsen K, Strommenger B, Walther B, Wieler L and Witte W (2010). Emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different animal species. International Journal of Microbiology 300:109-117.
Czaplewski L, Bax R, Clokie M, Dawson M, Fairhead H, Fischetti VA, Foster S, Gilmore BF, Hancock RE, Harper D, Henderson IR, Hilpert K, Jones BV, Kadioglu A, Knowles D, Ólafsdóttir S, Payne D, Projan S, Shaunak S, Silverman J, Thomas CM, Trust TJ, Warn P and Rex JH (2016). Alternatives to antibiotics-A pipeline portfolio review. Lancet Infectious Diseases 16(2):239-251.
Das Gunjan, Lalnunpuia C, Sarma K, Behera SK, Dutta TK and Bandyopadhyay Samiran (2015). Prevalence of Staphylococcus aureus associated sub-clinical mastitis in crossbred cows in Mizoram. Ruminant Science 4(2):167-170.
Diwakar, Akriti, Choudhary Sunita, Meena Dhirendra, Bhati Taruna and Kataria AK (2019). Antibiotic sensitivity pattern of some Staphylococcus aureus isolates from milk from goats with clinical mastitis. Ruminant Science 8(1):19-22.
Doot Manisha, Gaurav Abhishek, Solanki Sudeep, Chavhan Dinesh M and Bairwa Vipin Chand (2022). Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from bovine subclinical mastitic milk in Udaipur district, Rajasthan. Ruminant Science 11(1):79-82.
Dubal ZB, Rahman H, Murugkar HV, Kumar A, Shome BR, Shome R and Mukharjee R (2005). Characterization of Escherichia coli isolates from piglet diarrhoea. Indian Journal of Animal Science 75(12):1388-1389.
Dubal ZB, Avasthe RK, Haque N, Toppo S, Murugkar HV and Barbuddhe SB (2009). Efficacy of medicinal plant extracts and antimicrobials on different serotypes of Escherichia coli. Indian Journal of Animal Science 79(1):13-16.
EARS-Net (European Antimicrobial Resistance Surveillance Network) (2014). EARS-Net Report, Quarters 1-4. Dublin.
EFSA (European Food Safety Authority) (2009). Scientific opinion of the panel on biological hazards on a request from the European Commission on Assessment of the Public Health Significance of methicillin resistant Staphylococcus aureus (MRSA) in animals and foods. European Food Safety Authority Journal 993:1-73.
FDA (2010). Summary report on antimicrobials sold or distributed for use in food producing animals, 2009. Washington.
Fishovitz J, Hermoso JA, Chang M and Mobashery S (2014). Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus. IUBMB Life 66(8):572-577.
Galav Vikas, Galav Alka and Sharma Sandeep Kumar (2022). Isolation and antibiotic sensitivity profiling of Escherichia coli and Klebsiella spp. isolates from pneumonic lungs of sheep and goats. Ruminant Science 11(1):243-250.
Gaurav A, Gill JPS, Aulakh RS and Bedi JS (2014). ELISA based monitoring and analysis of tetracycline residues in cattle milk in Punjab. Veterinary World 7(1):26-29.
Ghatak S, Singha A, Sen A, Guha C, Ahuja A, Bhattachaijee U and Dey TK (2013). Detection of New Delhi metallo beta lactamase and extended spectrum beta lactamase genes in Escherichia coli isolated from mastitic milk samples. Transboundary Emerging Diseases 60:385-389.
Ghosh M, Wahi S, Kumar M and Ganguli A (2007). Prevalence of enterotoxigenic Staphylococcus aureus and Shigella spp. in some raw street vended Indian foods, International Journal of Environmental Health Research 17:151-156.
Goffin C and Ghuysen JM (1998). Multimodular penicillin binding proteins: An enigmatic family of orthologs and paralogs. Microbiology Molecular Biology Review 62:1079-1093.
Gopal S and Divya KC (2017). Can methicillin-resistant Staphylococcus aureus prevalence from dairy cows in India act as potential risk for community-associated infections?: A review. Veterinary World 10(3):311-318.
Gupta A, Nelson JM, Barrett TJ, Tauxe RV, Rossiter SP, Friedman CR, Joyce KW, Smith KE, Jones TF, Hawkins MA, Shiferaw B, Beebe JL, Vugia DJ, Rabatsky-Ehr T, Benson JA, Root TP and Angulo FJ (2004). Antimicrobial resistance among Campylobacter strains, United States, 1997-2001. Emerging Infectious Diseases 10(6):1102-1109.
Hao H, Sander P, Iqbal Z, Wang Y, Cheng G and Yuan Z (2016). The risk of some veterinary antimicrobial agents on public health associated with antimicrobial resistance and their molecular basis. Frontier in Microbiology 18(7):1626.
Ito T, Katayama Y and Hiramatsu K (1999). Cloning and nucleotide sequence determination of the entire mec DNA of pre methicillin resistant Staphylococcus aureus N315. Antimicrobial Agents Chemotherapy 43:1449-1458.
Jacoby GA and Munoz-Price LS (2005). The new beta-lactamases. New England Journal of Medicine 352:380-391.
Jaibhaye CS, Bhikane AU, Masare PS and Bhonsle AV (2020). Clinico-diagnostic and therapeutic investigations on pneumonia in cattle. Ruminant Science 9(1):25-32.
Jaipal J, Kumar V and Chaudhary ML (2022). Assess the knowledge of dairy farmers towards antibiotic usage at dairy farm. Ruminant Science 11(1):89-92.
Juya QA, Kaur P, Parmar M, Sharma NS and Arora AK (2022). Antibiotic resistance studies in Staphylococcus aureus isolates from goat milk. Ruminant Science 11(2):445-454.
Kapadiya DK, Joshi DV, Shah NM and Panchasara HH (2012). Serotyping and in vitro drug sensitivity of Escherichia coli isolated from neonatal buffalo calves with diarrhoea. Ruminant Science 1(2):141-143.
Kaushik P, Anjay, Kumari S, Bharti SK and Dayal S (2014). Isolation and prevalence of Salmonella from chicken meat and cattle milk collected from local markets of Patna, India. Veterinary World 7(2): 62-65.
Khan R, Islam B, Akram M, Shakil S, Ahmad A, Ali SM, Siddiqui M and Khan AU (2009). Antimicrobial activity of five herbal extracts against multi drug resistant (MDR) strains of bacteria and fungus of clinical origin. Molecules 14(2):586-597.
Kocaoglu O, Tsui HC, Winkler ME and Carlson EE. (2015). Profiling of beta-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. Antimicrobial Agents Chemotherapy 59(6):3548-3555.
Koovapra S, Bandyopadhyay S, Das G, Bhattacharyya D, Banerjee J, Mahanti A, Samanta I, Nanda PK, Kumar A, Mukherjee R, Dimri U and Singh RK (2016). Molecular signature of extended spectrum beta-lactamase producing Klebsiella pneumoniae isolated from bovine milk in eastern and north-eastern India. Infection Genetics and Evolution 44:395-402.
Koya SF, Ganesh S, Selvaraj S, Wirtz VJ, Galea S, Rockers PC (2022). Antibiotic consumption in India: Geographical variations and temporal changes between 2011 and 2019, JAC-Antimicrobial Resistance, Volume 4, Issue 5, October 2022, dlac112, https://doi.org/10.1093/jacamr/dlac112
Kumar R, Yadav BR, Anand SK and Singh RS (2011). Molecular surveillance of putative virulence factors and antibiotic resistance in Staphylococcus aureus isolates recovered from intra mammary infections of river buffaloes. Microbial Pathogenesis 51:31-38.
Kumar Vaibhav, Patel JS, Patel BR, Mevada VK and Raval AP (2012). Therapeutic efficacy of antimicrobial drugs in clinical mastitis of cross bred cattle. Ruminant Science 1(2):177-180.
Kuroda M, Nagasaki S, Ito R and Ohta T (2007). Sesquiterpene famesol as a competitive inhibitor of bpase activity of Staphylococcus aureus. FEMS Microbiology Letters 273:28-34.
Lalzampuia H, Dutta TK, Warjri I and Chandra R (2013). PCR-based detection of extended-spectrum beta-lactamases (blaCTX-M-1 and blaTEM ) in Escherichia coli, Salmonella spp. and Klebsiella pneumoniae isolated from Pigs in North Eastern India (Mizoram). Indian Journal of Microbiology 53 (3):291-296.
Lee JH (2006). Occurrence of methicillin resistant Staphylococcus aureus strains from cattle and chicken, and analyses of their mecA, mecRl and mecl genes. Veterinary Microbiology 114:155- 159.
Lim D and Strynadka NC (2002). Structural basis for the p lactam resistance of PBP2a from methicillin resistant Staphylococcus aureus. Nature Structural and Molecular Biology 9:870-876.
Malaviya Sanjay G, Kalyani IH, Sharma KK, Sakhare PS and Patel DR (2017). Prevalence of toxigenic Escherichia coli (E.coli) and rotavirus among neonatal calves in south Gurarat region (India) using classical and PCR based methods. Ruminant Science 6(1):139-144.
Marshall BM and Levy SB (2011). Food animals and antimicrobials: Impacts on human health. Clinical Microbiology Reviews 24:718-733.
Martínez-Martínez L, Pascual A, García I, Tran J and Jacoby GA (2003). Interaction of plasmid and host quinolone resistance. Journal of Antimicrobial Chemotherapy 51(4):1037-1039.
Naik VK, Shakya S, Patyal A, Gade NE and Bhoomika (2015). Isolation and molecular characterization of Salmonella spp. from chevon and chicken meat collected from different districts of Chhattisgarh, India. Veterinary World 8(6):702-706.
Neelam, Jain VK, Singh M, Joshi VG, Chhabra R and Singh K (2022). Virulence and antimicrobial resistance gene profiles of Staphylococcus aureus associated with clinical mastitis in cattle. PLoS ONE 17(5): e0264762.
Nirala RK, Anjana K, Mandal KG and Jayachandran C (2017). Persistence of antibiotic residue in milk under the region of Bihar, India. International Journal of Current Microbiology and Applied Sciences 6(3):2296-2299.
Nirupama KR, Vinodh Kumar OR, Pruthvishree BS, Sinha DK, Murugan MS, Krishnaswamy N and Singh BR (2018). Molecular characterisation of blaOXA48 carbapenemase, extended spectrum beta-lactamase (ESBL) and Shiga toxin producing Escherichia coli isolated from farm piglets of India. Journal of Global Antimicrobial Resistance 13:201-205.
Pinho MG, de Lencastre H and Tomasz A (2001). An acquired and a native penicillin binding protein cooperate in building the cell wall of drug resistant staphylococci. Proceedings of the National Academy of Sciences 98:10886-10891.
Parasana DK, Javia BB, Fefar DT, Barad DB and Ghodasara SN (2021). Molecular characterization and antimicrobial-resistant pattern of Streptococcus species isolated from bovine mastitis in and around Junagadh district. Ruminant Science 10(2):247-252.
Poojitha R, Shrivastav A, Kumar N, Shrivastav N, Singh SK and Ranjan R (2022). Study of antibiotic resistance pattern in isolated extended spectrum beta-lactamase producing bacteria from milk of healthy cattle. Ruminant Science 11(1):187-192.
Prashanth K, Rao KR, Reddy PV, Saranathan R and Makki AR (2011). Genotypic characterization of Staphylococcus aureus obtained from humans and bovine mastitis samples in India. Journal of Global Infectious Diseases 3(2):115-22.
Pruthvishree BS, Vinodh Kumar OR, Sinha DK, Malik YPS, Dubal ZB, Desingu PA, Shivakumar M and Krishnaswamy SB (2017). Spatial molecular epidemiology of carbapenem-resistant and New Delhi metallo beta-lactamase (blaNDM)-producing Escherichia coli in the piglets of organized farms in India. Journal of Applied Microbiology 122(6):1537-1546.
Rahman S, Ali T, Ali I, Khan NA, Han B and Gao J (2018). The growing genetic and functional diversity of extended spectrum beta-lactamases. BioMed Research International. https://doi.org/10.1155/2018/9519718
Rammelkamp C and Maxon Thelma (1942). Resistance of Staphylococcus aureus to the Action of Penicillin. Proceedings of the Society for Experimental Biology and Medicine.
Raorane Abhay, Chothe Shubhadha, Dubal ZB, Barbuddhe SB, Karunakaran M, Doijad Swapnil, Pathak Ajay, Poharkar Krupali and Singh NP (2013). Antimicrobial resistance of the pathogens isolated from bovine mastitis in Goa. Ruminant Science 2(2):139-144.
Ratova M and Mills A (2015). Antibacterial titania-based photocatalytic extruded plastic films, Journal of Photochemistry and Photobiology A: Chemistry 299:159-165.
Ruban S Wilfred, Babu R Narendra, Porteen K, Senthilkumar TMA, Raja P, Kumarasamy P, Ramakrishnan C and Abraham Robinson JJ (2017). Antimicrobial susceptibility pattern of Staphylococcus aureus isolates from mutton marketed in Chennai, India. Ruminant Science 6(1):145-148.
Robinson DA (1981). Infective dose of Campylobacter jejuni in milk. British Medical Journal 282:1584.
Ruiz-Palacios GM (2007). The health burden of Campylobacter infection and the impact of antimicrobial resistance: Playing chicken. Clinical Infectious Diseases 44:701-703.
Rukmini S (2024). ‘Mortality in India.’ Published on dataforindia.com
Rupp ME and Fey PH (2003). Extended spectrum beta-lactamase producing Enterobacteriaceae. Drugs 63: 353-365.
Samanta I, Joardar SN, Das PK and Sar TK (2015). Comparative possession of shiga toxin, intimin, enterohaemolysin and major extended spectrum beta lactamase (ESBL) genes in Escherichia coli isolated from backyard and farmed poultry. Iranian Journal of Veterinary Research 16(1):90.
Scallan E, Hoekstra RM, Angulo FJ, TauxeRV, Widdowson MA, Roy SL, Jones JL and Griffin PM (2011). Foodborne illness acquired in the United States major pathogens. Emerging Infectious Diseases 17.
Shahid M, Sobia F, Singh A and Khan HM (2012). Concurrent occurrence of blaampC families and blaCTX-M genogroups and association with mobile genetic elements ISEcpl, IS26, ISCR1, and sull-type class 1 integrons in Escherichia coli and Klebsiella pneumoniae isolates originating from India. Journal of Clinical Microbiology 50:1779-1782.
Shikha Deep, Wazir Virendera Singh, Rashid Mohd and Gazal Sabahat (2021). Phenotypic and genotypic characterization of extended spectrum beta-lactamases producing Klebsiella pneumoniae in bovines from Jammu region, India. Ruminant Science 10(2):253-259.
Shrivastav A, Sharma RK, Sahni YP, Shrivastav N, Gautam V and Jain S (2016). Study of antimicrobial resistance due to extended spectrum beta-lactamase-producing Escherichia coli in healthy broilers of Jabalpur. Veterinary World 9(11):1259-1263.
Singh BR, Vidya Singh, N Ebibeni and Singh RK (2013). Antimicrobial and herbal drug resistance in enteric bacteria isolated from faecal droppings of common house lizard/gecko (Hemidactylus frenatus). International Journal of Microbiology https://doi.org/10.1155/2013/340848
Sivakumar M, Dubal ZB, Kumar A, Bhilegaonkar KN, Vinodh Kumar OR, Kumar S, Anukampa Shagufta Bi, Grace MR, Ramees TP and Dwivedi A (2019). Virulent methicillin-resistant Staphylococcus aureus (MRSA) in street vended foods. Journal of Food Science and Technology 56:1116-1126.
Sivakumar M, Abass G, Vivekanandhan R, Singh DK, Bhilegaonkar KN, Suman Kumar M, Grace MR and Dubal ZB (2020). Extended-spectrum beta-lactamase (ESBL) producing and multidrug-resistant Escherichia coli in street foods: A public health concern. Journal of Food Science and Technology 58(4):1247-1261
Smith KE, Sansa TI and Coker AO (1999). Antibiotic susceptibility pattern and beta-lactamase production of animal and human isolates of Campylobacter in Lagos, Nigeria. Verlag Zeitschrift Naturforsch 54c:583-586.
Suman Kumar M, Ramees TP, Dhanze H, Gupta S, Dubal ZB and Kumar A (2021). Occurrence and antimicrobial resistance of Campylobacter isolates from broiler chicken and slaughter house environment in India. Animal Biotechnology 34(2):199-207.
Sunita, Diwakar and Kataria AK (2017). Antibiotic resistance pattern of Staphylococcus aureus isolated from milk of cattle with clinical mastitis. Ruminant Science 6(2):319-322.
Tasho RP and Cho JY (2016). Veterinary antibiotics in animal waste, its distribution in soil and uptake by plants: A review. Science of the Total Environment 563, 366-376.
Tesch W, Strassle A, Berger-Bachi B, O’Hara D, Reynolds P and Kayser F (1988). Cloning and expression of methicillin resistance from Staphylococcus epidermidis in Staphylococcus camosus. Antimicrobial Agents Chemotherapy 32:1494-1499.
Van Boeckel TP, Brower C, Gilbert M, Grenfell BT, Levin SA, Robinson TP, Teillant A and Laxminarayan R (2015). Global trends in antimicrobial use in food animals. Proceedings of the National Academy of Sciences 112:5649-5654.
Verma Kritika, Kansal SK and Singh Jaswinder (2022). Rational self-medication practices among dairy farmers: An exploratory study. Ruminant Science 11(2):387-392.
Vivekanandhan R, Malla BA, Milton AAP, Madesh A, Kale BM, Anukampa K, Vinodhkumar OR, Suman Kumar M and Dubal ZB (2022). Occurrence, antimicrobial resistance and virulence properties of thermophilic Campylobacter coli originating from two different poultry settings. Gene Reports 27:101618
Waters AE, Contente-Cuomo T, Buchhagen J, Liu CM, Watson L, Pearce K, Foster JT, Bowers J, Driebe EM and Engelthaler DM (2011). Multidrug resistant Staphylococcus aureus in US meat and poultry. Clinical Infectious Diseases 52:1227-1230.