16-Title: Differential haemato-biochemical response in genetically resistant and susceptible Jamunapari goats to Haemonchus contortus
Authors: Jitendra Tiwari, Daya Shanker, Dinesh Kumar Sharma and Souvik Paul
Source: Ruminant Science (2022)-11(1):73-77.
How to cite this manuscript: Tiwari Jitendra, Shanker Daya, Sharma Dinesh Kumar and Paul Souvik (2022). Differential haemato-biochemical response in genetically resistant and susceptible Jamunapari goats to Haemonchus contortus. Ruminant Science 11(1):73-77.
The study was carried out to compare the haemato-biochemical parameters in genetically resistant and susceptible Jamunapari goats after experimental infection with Haemonchus contortus. Resistant and susceptible kids below six months’ age were selected from a pure breed farm of Jamunapari goats based on the sire index along with their individual performance. A significantly (P<0.05) high faecal egg count was recorded in the susceptible group compared to the resistant group after a challenge dose of 25,000 infective larval stage of Haemonchus contortus. In animals susceptible to the infection significantly (P<0.05) decreases levels of Hb, RBC, PCV, TEC, serum glucose, total protein and albumin were recorded whereas serum ALP level was found significantly (P<0.05) increased in the susceptible group as compared to resistant animals. However, no significant difference was recorded for WBC, MCV, RDW, MCH, MCHC, Creatinine, BUN, ALT and AST. The study revealed higher resilience level is present in resistant animals compared to susceptible animals against the parasitic infection and they are able in maintaining normal blood parameters even after the high challenge dose of infective larvae. Increased ALP levels in Haemonchus contortus infection indicate its potential as a biomarker of the infection. This study will help develop a GIN-resistant line of the breed for sustainable control of the parasites.
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