25-Title: Evaluation of therapeutic potential of Dalbergia sissoo and Punica granatum on clinical cases of calf diarrhoea
Authors: Himanshu Agrawal, Arvind Kumar Tripathi, Ashish Srivastava, Ambika Sharma, PN Panigrahi, Manu Jaiswal and Shubhasini Dhuriya
Source: Ruminant Science (2021)-10(2):367-374.
How to cite this manuscript: Agrawal Himanshu, Tripathi Arvind Kumar, Srivastava Ashish, Sharma Ambika, Panigrahi PN, Jaiswal Manu and Dhuriya Shubhasini (2021). Evaluation of therapeutic potential of Dalbergia sissoo and Punica granatum on clinical cases of calf diarrhoea. Ruminant Science 10(2):367-374.
Abstract
Present study was conducted on 24 diarrhoeic calves and 6 healthy calves of Sahiwal breed aged up to one month to evaluate the therapeutic potential of Dalbergia sissoo and Punica granatum. After shed drying of leaves of Dalbergia sissoo and peel of Punica granatum powder was prepared. The diarrhoeic calves were divided in four treatment groups T1, T2, T3 and T4, and one group was the healthy control group (Hc). The powder was supplemented at the dose rate of 50gm bid for five days. In addition to powder Ringer lactate fluid @ of 25 ml/kg IV along with antiinflammatory and multivitamin were administered. The therapeutic efficacy of the above therapeutic regimens was evaluated based on clinical recovery (days of recovery) and improvement in the altered values of the clinical score, haemato-biochemical alterations and electrolyte values towards normalcy (as par to the values in healthy control calves) on day 6th after treatment. Clinical observations and blood sampling were done on the day of occurrence of diarrhoea and on day 6th post-treatment. Blood samples were collected on day 0 and day 6th, from the jugular vein in clean glass tubes for haemato-biochemical alterations before treatment. Complete blood count was done by haematology analyzer. A total of 5 ml blood was collected from each animal in a sterilized glass tube at each of the specified intervals for serum biochemistry. Blood was allowed to coagulate by keeping the tubes in slants and serum was separated by spinning at 3000 rpm for 10 minutes. Therapeutic regimen adopted in the treatment of acute diarrhoeic calves under groups T5 in which Dalbergia sissoo and Punica granatum powder were given was found to be most efficacious as evident by the improvement in clinical score in terms of rehydration, improved faecal consistency, depression score and improved haemato-biochemical alteration.
Reference
Cho Y and Yoon KJ (2014). An overview of calf diarrhoea-infectious etiology, diagnosis, and intervention. Journal of Veterinary Science 15:1-17.
Constable PD, Gohar HM, Morin DE and Thurmon JC (1996). Use of hypertonic saline dextran solution to resuscitate hypovolemic calves with diarrhoea. American Journal of Veterinary Research 57:97-104.
Dadawala AI, Chandel BS, Chauhan HC and Bhagat AG (2013). Molecular detection of bovine rotavirus from north Gujarat, India. Ruminant Science 2(2):131-137.
Delirezh N, Norian R and Azadmehr A (2016). Changes in some pro-and anti-inflammatory cytokines produced by bovine peripheral blood mononuclear cells following foot and mouth disease vaccination. Archives of Razi Institute 71:199-207.
Dubey GK, Gehlaut BS and Rao KNP (1992). Some observation on the serum protein profiles in experimental bovine colibacillosis. Indian Veterinary Journal 69:408-410.
Duncan JR, Keith WP and Eduiard AM (1994). Veterinary Laboratory Medicine and Clinical Pathology. 3rd Edn, Iowa State University Press, Ames, Iowa USA.
El-Tahawy Abdelgawad Salah and Mostafa Ibrahim Ahmed (2015). Prevalence, risk factors and cross sectional epidemiology for some selected diseases and syndromes affecting Rahmani sheep with particular spotlight on their economic consequences. Ruminant Science 4(2):159-165.
Fernandes CE, Roy K, Shukla PC and Rao MLV (2009). Changes in the haematological profile in calf diarrhoea in response to therapy. Intas Polivet 10:214-215.
Ghanem MM, Fkhrany SF, Abd El-Roaf YM and El-Attar HM (2012). Clinical and haematological evaluation of diarrhoeic neonatal buffalo calves (Bubalus bubalis) with reference to antioxidant changes. Benha Veterinary Medicine Journal 23:275-288.
Grove-White DH and White DG (1999). Abdominal distension in collapsed diarrhoeic calves: Biochemical finding and treatment. Veterinary Research 144:639-642.
Gupta P (2015). Efficacy of Psidium Guajava (Guava) leaves as an antidiarrhoeal in calves with special reference to E. coli. MVSc Thesis submitted to NDVSU, Jabalpur.
Gupta R (2016). Therapeutic efficacy of herbal formulations in diarrhoeic calves. MVSc Thesis submitted to NDVSU, Jabalpur.
Guzelbektes H, Coskun A and Sen I (2006). Relationship between the degree of dehydration and the balance of acid-based changes in dehydrated calves with diarrhoea. Bulletin of the Veterinary Institute in Pulawy 51:83-87.
Kapadiya DK, Joshi DV, Shah NM and Panchasara HH (2012). Serotyping and in vitro drug sensitivity of Escherichia Coli isolated from neonatal buffalo calves with diarrhoea. Ruminant Science 1(2):141-143.
Kapadiya DK, Joshi DV, Chaudhary SS, Shah NM, Panchasara HH and Patel BJ (2012). Diagnosis of rotavirus infection in neonatal calves by ribose nucleic acid polyacrylamide electrophoresis (RNA-PAGE) and double antibody sandwich enzyme linked immunosorbent assay (DAS-ELISA). Ruminant Science 1(1):15-18.
Kasimanickam RK, Kasimanickam VR, Olsen JR, Jeffress EJ, Moore DA and Kastelic JP (2013). Associations among serum pro-and anti-inflammatory cytokines, metabolic mediators, body condition, and uterine disease in postpartum dairy cows. Reproductive Biology and Endocrinology 11:103.
Kaur K, Randhawa SS and Chhabra S (2006). Haemato-biochemical profile of diarrhoeic dairy calves affected with colibacillosis. Indian Journal of Veterinary Medicine 26:9-11.
Malaviya Sanjay G, Kalyani IH, Sharma KK, Sakhare PS and Patel DR (2017). Prevalence of toxigenic Escherichia coli (E.Coli) and rotavirus among neonatal calves in south Gurarat region (India) using classical and PCR based methods. Ruminant Science 6(1):139-144.
Mir N (2009). Rehydration and herbal therapy in calf diarrhoea. MVSc Thesis submitted to Jawaharlal Nehru Krishi Vishwa Vidyalaya, Jabalpur.
Murtaugh MP, Baarsch MJ, Zhou Y, Scamurra RW and Lin G (1996). Inflammatory cytokines in animal health and disease. Veterinary Immunology and Immunopathology 54:45-55.
Nayak TC, Singh AP, Savita, Yadav R, Gupta SR and Kachhawa JP (2019). Studies on prevalence and risk factors associated with colibacillosis in cattle calves in Bikaner. Ruminant Science 8(1):89-92.
Opal SM and De Palo VA (2000). Anti-inflammatory cytokines. Chest 117:1162-1172
Ouyang W, Rutz S, Crellin NK, Valdez PA and Hymowitz SG (2011). Regulation and functions of the IL10 family of cytokines in inflammation and disease. Annual Review of Immunology 29:71-109.
Radostits OM, Gay CC, Blood DC and Hinchcliff KW (2010). Disease of the alimentary tract. Veterinary Medicine. 10th Edn, Saunders, London, pp 99-100.
Shaheen M, Pampori AZ, Matto AF and Shah AR (2002). Neonatal calf enteritis in Kashmir and its management. Indian Veterinary Journal 79:723-724.
Sharma PC, Yelne MB and Dennis TJ (2001). Database on medicinal plants used in Ayurveda. Vol 2. New Delhi: Central Council for Research in Ayurveda and Siddha; pp 481-9.
Sharma SK, Joshi Monika and Tanwar RK (2017). Evaluation of various therapeutic regimens for the treatment of calf diarrhoea. Ruminant Science 6(2):383-388.
Snedecor GW and Cochran WG (1994). Statistical Methods. 8th Edn, Iowa State Press, Iowa, USA
Tikoo A, Soodan JS, Singh G and Singh I (2017). Effect of various therapeutic regimens on the treatment of calf diarrhea and their effect on various clinico, hematobiochemical parameters. International Journal of Livestock Research 7:174-183.
Walker PG, Constable PD, Morin DE, Foreman JH, Drackley JK and Thurmon JC (1998). Comparison of hypertonic saline-dextran solution and lactated ringer’s solution for resuscitating severely dehydrated calves with diarrhoea. Journal of American Veterinary Medical Association 213:113-122.