31-Title: Modulation of serum cholesterol, AST, glucose and fertility outcomes following uterine lavage, and parenteral administration of levamisole, cloprostenol and their combinations in endometritic buffaloes

31-Title: Modulation of serum cholesterol, AST, glucose and fertility outcomes following uterine lavage, and parenteral administration of levamisole, cloprostenol and their combinations in endometritic buffaloes

Authors: Narendra Singh, Bhoopendra Singh and Rajesh Kumar

 Source: Ruminant Science (2023)-12(1):153-156.

How to cite this manuscript: Singh Narendra, Singh Bhoopendra and Kumar Rajesh (2023). Modulation of serum cholesterol, AST, glucose and fertility outcomes following uterine lavage, and parenteral administration of levamisole, cloprostenol and their combinations in endometritic buffaloes. Ruminant Science 12(1):153-156.


The objective of this study was to compare the effect of uterine lavage, and parenteral administration of Levamisole (s/c), PGF2alpha (i/m) and their combinations on blood biochemistry and fertility outcomes in endometritic buffaloes. Thirty-six repeat breeder buffaloes were randomly assigned into six groups. Six animals were kept as positive control (G0, no treatment, only sexual rest), and the rest were assigned to five treatment groups, i.e., G1 (Uterine Lavage), G2 (Levamisole s/c), G3 (Cloprostenol i/m), G4 (Uterine Lavage + Levamisole s/c) and G5 (Uterine Lavage + Cloprostenol i/m). After treatment significant (p<0.05) drops in serum cholesterol and AST level were noted, whereas a significant increase in glucose level was recorded in all five treatment groups. The clinical cure rate was observed as 33.33, 50.00, 66.67, 66.67, 83.33 and 83.33% in G0, G1, G2, G3, G4 and G5, respectively. The corresponding conception rates were 16.67, 33.33, 50.00, 50.00, 66.67 and 66.67 %. The results inferred that uterine lavage along with levamisole or cloprostenol can be used effectively to manage endometrtitic buffaloes.


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