5-Title: EVALUATING THE EFFECTIVENESS OF HERBAL FORMULATIONS IN CONVENTIONAL TREATMENT FOR LUMPY SKIN DISEASE (LSD) IN CATTLE: A COMPARATIVE FIELD STUDY
Authors: B Dhanvandhini, M Sakthi Priya and R Deva
Source: Ruminant Science (2025)-14(2):135-138.

Abstract

How to cite this manuscript: Dhanvandhini B, Priya M Sakthi and Deva R (2025). Evaluating the effectiveness of herbal formulations in conventional treatment for lumpy skin disease (LSD) in cattle: A comparative field study. Ruminant Science 14(2):135-138.
Abstract
Lumpy skin disease (LSD) is an economically significant viral disease of cattle caused by the lumpy skin disease virus (LSDV), a member of the Capripoxvirus genus. The present study was conducted as a farm trial at Pondicherry and evaluated the effectiveness of herbal formulations as an adjunct to conventional treatment in LSD-affected cattle. A total of 30 cattle were selected and divided into three groups with 10 animals in each: Group A (conventional allopathic treatment), Group B (conventional treatment plus herbal formulation), and Group C (conventional treatment plus a commercially available oral LSD booster). Recovery parameters, including feed intake restoration and time taken for healing wound lesions, were assessed. Statistical analysis demonstrated that Group B exhibited significantly faster recovery than Groups A and C (P<0.01). These findings highlight the potential of herbal formulations in improving recovery outcomes in LSD-infected cattle, necessitating further clinical investigation. References Alzohairy MA (2016). Therapeutics role of Azadirachta indica (neem) and their active constituents in diseases prevention and treatment. Evidence-based Complementary and Alternative Medicine: Article ID 7382506. Buller RM and Palumbo GJ (1991). Poxvirus pathogenesis. Microbiological Reviews 55:80-122. Dutta P, Kumar AH, Mahajan AC, Shroff S, Rana SK, Sahariah PJ, Gogoi P, Borah D, Punniamurthy N and Nair MNB (2022). Case reports on management of LSD like conditions with ethno-veterinary practices. Pharma Innovation Journal 11:236-239. Gupta T, Patial V, Bali D, Angaria S, Sharma M and Chahota R (2020). Lumpy skin disease and its emergence in India. Veterinary Research Communications 44:111-118. Kumari Rashmi Rekha, Tripathi Manoj Kumar, Kumar Ravi, Kumar Prabhas, Kumar Manish, Kumar Abhay, Sarma Kamal and Kumar Pankaj (2021). Intricacy in cross-bred cattle with presumptive lumpy skin disease and prospective antiviral role of ivermectin. Ruminant Science 10(2):375-382. Mathew D and Hsu WL (2018). Antiviral potential of curcumin. Journal of Functional Foods 40:692-699. Nayak BS, Isitor G, Davis EM and Pillai GK (2007). The evidence based wound healing activity of Lawsonia inermis Linn. Phytotherapy Research 21:827-831. Palai S, Kesh SS and Biswas S (2024). Ethnoveterinary approach in Lumpy Skin Disease (LSD): A review. Indian Journal of Animal Health 64:06-16. Prakash PAGN and Gupta N (2005). Therapeutic uses of Ocimum sanctum Linn (Tulsi) with anoteoneugenol and its pharmacological actions: A short review. Indian Journal of Physiology and Pharmacology 49:125. Salib FA and Osman AH (2011). Incidence of lumpy skin disease among Egyptian cattlein Giza Governorate, Egypt. Veterinary World 4(4). Sandeep, Yadav Dhawal Kant, Kumar Amit, Kachhawa JP, Gupta Sita Ram, Singh AP and Yadav Rajender (2023). Oxidative stress, immunological and systemic inflammatory changes in lumpy skin disease affected cattle. Ruminant Science 12(1):9-12. Sasi M, Kumar S, Kumar M, Thapa S, Prajapati U, Tak Y, Changan S, Saurabh V, Kumari S, Kumar A, Hasan M, Chandran D, Radha Bangar, Dhumal S, Senapathy M, Thiyagarajan A, Alhariri A, Dey A, Singh S, Prakash S, Pandiselvam R and Mekhemar M (2021). Garlic (Allium sativum L.) bioactives and its role in alleviating oral pathologies. Antioxidants 10:Article 1847. Sudhakar SB, Mishra N, Kalaiyarasu S, Jhade SK, Hemadri D, Sood R, Singh VP (2020). Lumpy skin disease (LSD) outbreaks in cattle in Odisha state, India in August 2019: Epidemiological features and molecular studies. Transboundary and Emerging Diseases 67:2408-2422. Takooree H, Aumeeruddy MZ, Rengasamy KR, Venugopala KN, Jeewon R, Zengin G and Mahomoodally MF (2019). A systematic review on black pepper (Piper nigrum L.): From folk uses to pharmacological applications. Critical Reviews in Food Science and Nutrition 59(Suppl 1):S210-S243. Tuppurainen ESM, Babiuk S and Klement E (2018). Lumpy skin disease. Springer 17:81. Windisch W, Schedle K, Plitzner C and Kroismayr A (2008). Use of phytogenic products as feed additives for swine and poultry. Journal of Animal Science 86::E140-E148. Wiseman H (2013). Phytochemicals: Health effects. In: Caballero, B. (Ed.), Encyclopedia of Human Nutrition(Third Edition). Academic Press, Waltham. pp 47-51. Yadav J, Venkatesh M, Lakshman M and Madhuri D (2021). A combination of conventional and alternative ethnoveterinary medicine for the treatment of lumpy skin disease in a she-buffalo: A case report. Pharma Innovation SP-10(1):83-84. Zahidin NS, Saidin S, Zulkifli RM, Muhamad II, Ya’akob H and Nur H (2017). A review of Acalyphaindica L. (Euphorbiaceae) as traditional medicinal plant and its therapeutic potential. Journal of Ethnopharmacology 207:146-173.