37-Title: Efficacy of Calendula officinalis with Curcuma longa for open wound in large ruminants
Authors: Sandeep Kumar, Ashok Kumar, Ankit Dangi, RN Chaudhary, Ram Niwas and Dinesh
Source: Ruminant Science (2020)-9(2):395-398.
How to cite this manuscript: Kumar Sandeep, Kumar Ashok, Dangi Ankit, Chaudhary RN, Niwas Ram and Dinesh (2020). Efficacy of Calendula officinalis with Curcuma longa for open wound in large ruminants. Ruminant Science 9(2):395-398.
The present study was conducted on eleven large ruminants (cattle and buffaloes) regardless of breed, age and sex with a history of large open wounds with no possibility of the suture. Most of the wounds were infected, large in size, and had no tendency to heal with routine clinical treatment. Animals were treated with topical application of 10% Calendula officinalis (mother tincture) with 10% Curcuma longa in glycerine base twice a day at institute hospital. While under field condition, animals were treated with a paste of turmeric powder in fresh calendula petal juice twice a day. Post-treatment follow up was taken up to complete wound healing. Wound healing properties of Calendula officinalis with Curcuma longa found to be effective for massive open wounds in ruminants.
Amirghofran Z, Azadbakht M and Karimi M (2000). Evaluation of the immunomodulatory effects of five herbal plants. Journal of Ethnopharmacology 72:167-172.
Brown D and Dattner A (1998). Phytotherapeutic approaches to common dermatological conditions. Archives of Dermatology 134(11):1401-4.
Chun KS, Keum YS, Han SS, Song YS, Kim SH and Surh YJ (2003). Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NFkappaB activation. Carcinogenesis 24:1515.
Della LR, Tubaro A, Sosa S (1994). The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Planta Medica 60(6):516-520.
Garg SL, Sharma NK, Rajput DS and Rathore SS (2019). Ethnoveterinary practices of gynaecological affection with their extent of use in western zone of Rajasthan. Ruminant Science 8(1):69-72.
Gilchrist B (1994). Treating bacterial wound infection. Nursing Times 90(50):55-56, 58.
Gopinath D, Ahmed MR, Gomathi K, Chitra K, Sehgal PK and Jayakumar R (2004). Dermal wound healing processes with curcumin incorporated collagen films. Biomaterials 25:1911.
Grandjean-Laquerriere A, Gangloff SC, Le Naour R, Trentesaux C, Hornebeck W and Guenounou M (2002). Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes. Cytokine 18:168.
Hey B (1996). The illustrated book of herbs. England: New Holland Publishers.
Iauk L, Lo Bue A and Milazzo I (2003). Antibacterial activity of medicinal plant extracts against periodontopathic bacteria. Phytotherapy Research 17:599-604.
Kasiram K, Sakharkar P and Patil A (2000). Antifungal activity of Calendula officinalis. Indian Journal of Pharma Science 62(6):464-466.
Kumar S, Kumar A, Chaudhary RN, Niwas R, Kumar A and Dishant (2019). Efficacy of Calendula officinalis for large open wound in animals. Pharma Innovation Journal 8(12):257-60.
Mani H, Sidhu GS, Kumari R, Gaddipati JP, Seth P and Maheshwari RK (2002). Curcumin differentially regulates TGF-beta1, its receptors and nitric oxide synthase during impaired wound healing. Biofactors 16:29.
Patrick K, Kumar S, Edwardson P and Hutchinson J (1996). Induction of vascularisation by an aqueous extracts of the flowers of Calendula officinalis L. the European marigold. Phytomedicine 3(1):8-11.
Paul S, Rahman ANMA, Abdullah-Al-Mahmud M, Uzzal AR and Das ZC (2017). Wound healing by marigold (Calendula officinalis) and turmeric (Curcuma longa) Paste: A comparative approach. Journal of Advanced Veterinary and Animal Research 4(4):333-342.
Sidhu GS, Singh AK and Thaloor D (1998). Enhancement of wound healing by curcumin in animals. Wound Repair and Regeneration 6:167.
Thangapazham RL, Sharad S and Maheshwari RK (2013). Skin regenerative potentials of curcumin. Biofactors 39:141.
Varljen J, Liptak A and Wagner H (1989). Structural analysis of a Rhamnoarabinogalactan and arabinogalactans with immuno-stimulating activity from Calendula officinalis. Phytochemistry 28(9):2379-2383.
Verma Abhishek, Kumar Dharmendra, Nema Anuradha, Sheikh TJ, Shukla Mansi, Ranjan Rajesh and Jain Payal (2020). Studies on the efficacy of fresh Aloe vera pulp on wound healing in calves. Ruminant Science 9(1):155-158.