Gas chromatography-mass spectrometry (GC-MS) analysis of ethanolic extract of Holarrhena antidysentrica stem bark (Pandhara kuda)
Title: Gas chromatography-mass spectrometry (GC-MS) analysis of ethanolic extract of Holarrhena antidysentrica stem bark (Pandhara kuda)
Authors: GC Panchbhai, NP Dakshinkar, GR Bhojne, SV Upadhye and PR Itankar
Source: Ruminant Science (2017)-6(1):85-87.
Cite this reference as: Panchbhai GC, Dakshinkar NP, Bhojne GR, Upadhye SV and Itankar PR (2017). Gas chromatography-mass spectrometry (GC-MS) analysis of ethanolic extract of Holarrhena antidysentrica stem bark (Pandhara kuda). Ruminant Science 6(1):85-87.
The use of plants and their preparations to treat variety of diseases is an age-old practice. Holarrhena antidysentrica which is locally know as “Pandhara kuda” is a native plant of India. It has been used traditionally for the treatment of dysentery especially amoebic dysentery. In the present study the ethanolic stem bark extract of Holarrhena antidysentrica is screened by GC-MS method. In this analysis, 22 bioactive phytochemical compounds were identified. These compounds are predominantly phenolic derivatives and included hydrocarbons, carbohydrates, fatty acid, fatty acid ester, alcoholic compounds, alkaloids, ketones and alkenes compounds. These different active phytochemicals have been found to possess a wide range of activities, especially effective against helminths.
Akhtar P, Mohd A, Sharma MP, Farooqi Humaira, Mir SR and Khan HN (2011). Development of quality standards of Holarrehena antidysenterica (Linn.) Bark. Recent Research in Science and Technology 3(1):73-80
Chakraborty A and Brantner AH (1999). Antibacterial steroid alkaloids from the stem bark of Holarrhena pubescens. Journal of Ethnopharmacology 15(1-3):339-44.
Shahzadi H, Khan ZH, Mular SM and Khan ND (2017). Phytochemical screening of Holarrhena antidysentrica. International Journal of Applied Research 3(1):560-561
Kavitha D, Shilpa PN, Devaraj S and Niranjali (2004). Antibacterial and antidiarrhoeal effects of alkaloids of Holarrhena antidysenterica WALL. Indian Journal of Experimental Biology 42:6
Kumar Sampath S and Rama Krishnan N (2007). Chromatographic fingerprint analysis of Naringi crenulata by HPTLC technique. Asian Pacific Journal of Tropical Biomedicine 1:S195-S-198.
Sinha S, Sharma A, Reddy PH, Rathi B, Prasad NVSRK and Vashishtha A (2013). Evaluation of phytochemical and pharmacological aspects of Holarrhena antidysenterica (Wall.): A comprehensive review. Journal of Pharmacy Research 6(4):488-492.
Zahin M, Aqil F and Ahmad I (2009). The in vitro antioxidant activity and total phenolic content of four Indian medicinal plants. International Journal of Pharmacy and Pharmaceutical Sciences 1:l.