Influence of parity, THI and HSPB1 gene SNP on heat tolerance indicator traits in murrah buffalo (Bubalus bubalis)

Influence of parity, THI and HSPB1 gene SNP on heat tolerance indicator traits in murrah buffalo (Bubalus bubalis)

Title: Influence of parity, THI and HSPB1 gene SNP on heat tolerance indicator traits in murrah buffalo (Bubalus bubalis)

Authors: Ashwani Arya, Archana Verma, ID Gupta, Dhaman Kumar, Ankit Magotra,

Mohsin Ayoub Mir and Arun Pratap Singh

Source: Ruminant Science (2016)-5(2):143-148.

Cite this reference as: Arya Ashwani, Verma Archana, Gupta ID, Kumar Dhaman, Magotra Ankit, Mir Mohsin Ayoub and Singh Arun Pratap (2016). Influence of parity, THI and HSPB1 gene SNP on heat tolerance indicator traits in murrah buffalo (Bubalus bubalis). Ruminant Science 5(2):143-148.

Abstract

Heat stress due to elevated temperature is a very important problem globally. The ultimate effect is on development, production and reproduction trait of animals. Breeding for heat stress tolerance can be mitigated by breeding animals having genotype that have improved levels of thermo-tolerance using different conventional and advanced genetic tools. Buffaloes exhibit signs of great heat stress when exposed to direct solar radiation and working in the sun during hot weather. Heat shock proteins (HSPs) expression has been correlated with resistance to stress and is considered as a potential indicator of animal adaptation to harsh environmental stress. HSP27 (HSPB1) gene is a candidate gene which plays an important role in thermotolerance, cytoprotection, chaperon activity and cell differentiation. The association with heat tolerance traits (respiration rate, rectal temperature and heat tolerance coefficient) were investigated in 100 Murrah buffaloes. One SNP in exon 1 at position 225 was confirmed in HSPB1 gene of Murrah buffalo. Effect of genotypes on RR, RT and HTC was not significant. Effect of THI and parity was significant for RT (P<0.0001). Heat tolerance coefficient (HTC) was also calculated to check the adaptability of the animals during the period of heat stress. THI had significant effect on RR, RT and HTC.

References

Arona SP, Bajpai LD and Muley AR (1962). Influence of dry period on milk yield and effects on lactation yield and lactation days of Murrah buffaloes. Journal of Veterinary and Animal Husbandry Resarch Mhow 5:51–55.

Arrigo AP (2007). The cellular networking of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis. Advances in Experimental Medicine and Biology 594:14-26.

Benezra MV (1954). A new index for measures the adaptability of cattle to tropical condition.  Journal of Animal Science 13:1015.

Borges JC and Ramos CH (2005). Protein folding assisted by chaperones. Protein and Peptide Letters 12(3):257-261.

Charette SJ, Lavoie JN, Lambert H and Landry J (2000). Inhibition of Daxx-mediated apoptosis by heat shock protein 27.  Molecular and Cellular Biology 20(20):7602-7612.

Collier RJ, Collier JL, Rhoads RP and Baumgard LH (2008). Genes involved in the bovine heat stress response.  Journal of Dairy Science 91:445-454.

Dash S, Chakravarty AK,  Sah V,  Jamuna V, Behera R,  Kashyap N and Deshmukh B (2015). Influence of temperature and humidity on pregnancy rate of murrah buffaloes under subtropical climate. Asian-Australas Journal of Animal Science 28(7): 943-950.

Dikmen S, Cole JB, Null DJ and Hansen PJ (2013). Genome-wide association mapping for identification of quantitative trait loci for rectal temperature during heat stress in Holstein cattle. PLoS One 8(7):e69202.

Hocquette JF, Bernard-Capel C, Vidal V, Jesson B, Levéziel H, Renand G and Cassar-Malek I (2012). The GENOTEND chip: a new tool to analyse gene expression in muscles of beef cattle for beef quality prediction. BMC Veterinary Research 8:135.

Kimura M and Crow JF (1964). The number of alleles that can be maintained in a finite population. Genetics 49:725-38.

Kumar R, Gupta ID, Verma A, Verma N and Vineeth MR (2015). Genetic polymorphisms within exon 3 of heat shock protein 90AA1 gene and its association with heat tolerance traits in Sahiwal cows. Veterinary World 8(7):932-936.

Lewontin RC (1972). Testing the theory of natural selection. Nature 236: 181-182.

McDowell RE, Hooven NW and Adcamoens JK (1976). Effects of climate on performance of Holsteins in first lactation. Journal of Dairy Science 59: 965-973.

Mohanarao GJ, Mukherjee A, Banerjee D, Gohain M, Dass G, Brahma B, Datt TK, Upadhyay RC and De S (2014). HSP70 family genes and HSP27 expression in response to heat and cold stress in vitro in peripheral blood mononuclear cells of goat (Capra hircus). Small  Ruminant Research 116:94-99.

National Research Council (1971). A Guide to Environmental Research on Animals. Washington, DC: National Academy of Sciences.

Parcellier A, Schmitt E, Gurbuxani S, Solary E and Garrido C (2003). Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways. Biochemical and Biophysical Research Communications 304:505-512.

Sambrook J and Russell D (2001). Molecular cloning: A Laboratory Manual 3rd edition. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.

Sarto C, Binz PA and Mocarelli P (2000). Heat shock proteins in human cancer. Electrophoresis 21(6):1218-1226.

Sevane N, Armstrong E, Wiener P, Pong Wong R and Dunner S (2014). Polymorphisms in twelve candidate genes are associated with growth, muscle lipid profile and meat quality traits in eleven European cattle breeds. Molecular Biology Report 41(7):4721-31.

Verma DN, Lal SN, Singh SP, Parkash OM and Parkash O (2000). Effect of season on biological responses   and productivity of buffalo. International Journal of Animal Science 15:237-244.

Verma N, Gupta ID, Verma A, Kumar R, Das R and Vineeth MR (2016). Novel SNPs in HSPB8 gene and their association with heat tolerance traits in Sahiwal indigenous cattle. Tropical Animal Health and Production 48:175-180.