Plasma leptin and biochemical profile around parturition in primiparous Sahiwal cows
Title: Plasma leptin and biochemical profile around parturition in primiparous Sahiwal cows
Authors: Vijay Pandey, Rajesh Nigam, Rambachan, Pawanjit Singh, SP Singh and AK Madan
Source: Ruminant Science (2016)-5(2):227-233.
Cite this reference as: Pandey Vijay, Nigam Rajesh, Rambachan, Singh Pawanjit, Singh SP and Madan AK (2016). Plasma leptin and biochemical profile around parturition in primiparous Sahiwal cows. Ruminant Science 5(2):227-233.
For studying the role of leptin hormone around parturition and to evaluate its association with other biochemical profile in high yielding primiparous Indian cow, six primiparous pregnant Sahiwal cows of same age group and body condition score were selected. The blood samples were collected from these cows on 30 day prepartum, day of parturition and on 30 day postpartum and plasma was harvested. The plasma samples were further analyzed for levels of leptin hormone, non-esterified fatty acids (NEFA), glucose, triglycerides (TG), cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), total plasma protein (TPP), albumin, urea, creatinine, calcium (Ca), phosphorus (P) and potassium (K). The results of plasma leptin, TG, cholesterol, HDL and LDL showed highest level of leptin in late pregnancy (-30 days) which significantly declined to nadir at parturition then rose around to prepartum levels at 30 days postpartum. The NEFA concentration increased from pregnancy to calving and later decreased to achieve prepartum
levels during lactation. The levels of plasma TPP, albumin, globulin and P were highest in pregnancy which declined to nadir at parturition and remained almost unchanged during lactation. Creatinine and Ca concentrations remained unchanged from pregnancy to parturition and then significantly reduced during lactation while urea was significantly lower during pregnancy and rose in lactation. The overall correlation of LEP with biochemical profile revealed positive correlation with TG (r = 0.8), cholesterol (r = 0.69), HDL (r = 0.67), LDL (r = 0.52), globulin (r = 0.56) and P (r = 0.59) while negative correlation with NEFA (r = -0.90) and AG ratio. In addition leptin showed negative correlation with creatinine during pregnancy and lactation. In conclusion, the variations in leptin hormone and other biochemical profiles from pregnancy to lactation, and association of leptin hormone with biochemical profile suggesting its significant physiological role in energy metabolism, body mass and immunity of dairy cows during this crucial period.
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