8-Title: Evaluation of health status by serum metabolic profiling in Rathi cows with some disorders
Authors: N Kataria and AK Kataria
Source: Ruminant Science (2012)-1(2):131-135.
How to cite this manuscript: Kataria N and Kataria AK (2012). Evaluation of health status by serum metabolic profiling in Rathi cows with some disorders. Ruminant Science 1(2):131-135.
Health status was evaluated in Rathi cows with some disorders viz. ketosis, diarrhoea, traumatic pericarditis and acidosis. The serum metabolic profiling included determination of various serum enzymes viz. sorbitol dehydrogenase, malate dehydrogenase, glucose-6-phosphate dehydrogenase, glutamate dehydrogenase, ornithine carbamoyltransferase, 5’nucleotidase, glucose-6-phosphatase, arginase, and aldolase in healthy animals, the mean values (UL-1) of which were 12.00±0.12, 42.00±1.21, 4.12±0.01, 23.00±0.76, 9.00±0.41, 17.00±1.00, 4.10±0.09, 11.00±0.06 and 10.01±0.06, respectively. When a comparison was made between values from healthy and animals with disorders it was deduced that there was a significant increase (p<0.05) in the levels of each of the enzymes in affected cows. The magnitude of increase in the levels of all the enzymes was maximum in the cows affected with ketosis in comparison to other disorders. Glucose-6-phosphatase showed a maximum of 3.43 times increase in cows having ketosis. It was concluded that modulation of metabolic reactions was there to meet the metabolic crisis in affected animals and a regular metabolic profiling can help in monitoring the health status of the cows affected with various disorders to check worsening of the conditions.
Abdel-Fattah M, Moussa SZ, El-Hindy HM and Gouda EM (2002). Gluconeogenic behaviour of camel hepatocytes (Camelus dromedarius) by using (1-C14) propionate and (1-C14) lactate as substrates. Journal of Camel Practice and Research 9(2):107-114.
Alemu P, Forsyth GW and Searcy GP (1977). A comparison of parameters used to assess liver damage in sheep treated with carbon tetrachloride. Canadian Journal of Comparative Medicine 41:420-427.
Hanson RW and Ballard FJ (1967). Lipid synthesis in liver and adipose tissue from ruminants. Biochemical Journal 105:529-529.
Herdt TH (2000). Variability characteristics and test selection in herd-level nutritional metabolic profile testing. Veterinary Clininic of North America: Food Animal Practice 16:387-403.
Greenberg D M (1960). Enzymes of urea cycle. In: Enzymes, Eds PD Boyer, H Lardy and K Myrback, 2nd Edn, Academic Press, New York, USA.
Geishauser T, Leslie KE, Duffield TF and Edge V (1997). Evaluation of aspartate transaminase activity and beta-hydroxybutyrate concentration in blood as tests for prediction of left displaced abomasum in dairy cows. American Journal of Veterinary Research 58:1216-1220.
Kataria N, Kataria AK, Chaturvedi M and Sharma A (2011). Changes in serum enzymes levels associated with liver functions in stressed Marwari goat. Journal of Stress Physiology and Biochemistry 7(1):13-19.
Kataria N, Kataria AK and Joshi A (2010). Fuelling of TCA cycle in hepatic cells of Marwari goat during ambient temperature associated stress. Journal of Stress Physiology and Biochemistry 6(4):5-11.
Kataria N and Kataria AK (2012). Assessment of stress due to hot ambience in donkeys from arid tracts in India. Journal of Stress Physiology and Biochemistry 6(4):12-17.
King J (1965). In: Practical Clinical Enzymology. D VanNostrand Company Ltd, London 1-301.
Kour G and Kataria N (2011). Ambient temperature associated variations in serum arginase and aldolase in Marwari goat. Veterinary Practitioner 12(1):124-127.
Krause K M and Oetzel GR (2006). Understanding and preventing subacute ruminal acidosis in dairy herds: A review. Animal Feed Science Technology 126:215-236.
Mori A, Urabe S, Asada M, Tanaka Y, Tazaki H, Yamamoto I, Kimura N, Ozawa T, Morris ST, Hickson R, Kenyon PR, Blair H, Choi CB and Arai T (2007). Comparison of plasma metabolite concentrations and enzyme activities in beef cattle raised by different feeding systems in Korea, Japan and New Zealand. Journal of Veterinary Medicine A Physiology, Pathology and Clinical Medicine 54:342-345.
Ramin AG, HashemiAsl M, Asri-Rezaie S, batebi E, Tamadon A and Ramin S (2011). Prediction of traumatic pericarditis in cows using some serum biochemical and enzyme parameters. Acta Veterinaria 61:383-390
Razmi N, Jelodar GA, Nazifi S and Dehghani A (2005). Arginase status in cattlereproductive system. Veterinarski Arhiv 75(1):31-38.
Steel RGD and Torrie JH (1980). In: Principles and Procedures of Statistics. A Biometrical Approach. 2ndEdn, McGraw-Hill Kogakusha Ltd, Tokyo pp187-190.
Stengärde L, Tråvén M, Emanuelson U, Holtenius K, Hultgren J and Niskanen R (2008). Metabolic profiles in five high-producing Swedish dairy herds with a history of abomasal displacement and ketosis. Acta Veterinaria Scandinavica 50:31 doi: 10.1186/1751-0147-50-31
vanSaun RJ (2004). Metabolic profiling to evaluate transition cow nutrition and health status. In: Proceedings 23rd World Buiatrics Congress, Quebec, Quebec, Canada, July 11-16, LeMedecinVeterinaire Du Quebec 34:122.
Varley H (1988). Tests in liver and biliary tract disease. In: Practical Clinical Biochemistry. CBS Publishers and Distributor, New Delhi, pp 158-467.
Wolf PL and Williams D (1973). In: Practical Clinical Enzymology. New York: Wiley-Inetrscience Publication, John Wiley and Sons pp 37-85.
Whitaker DA (2004). Metabolic profiles. In: Bovine Medicine: Diseases and Husbandry of Cattle. Eds Andrews AH, Blowey RW, Boyd H and Eddy RG, 2nd Edn, Oxford: Blackwell Science pp 804-817.
Yip MCM and Knox WE (1972). Function of arginase in lactating mammary gland. Biochemical Journal 127:893.